National projects

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1.03 Natural sciences and mathematics / Biology
1.04 Natural Sciences and mathematics/Chemistry
1.04.02 Natural sciences and mathematics / Chemistry / Structural chemistry
1.05 Natural sciences and mathematics/Biochemistry and molecular biology
1.07. Natural sciences and mathematics / Computer intensive methods and applications
1.09 Pharmacy
1-09 Natural sciences and Mathematics - Pharmacy
2.04 Ingeeniring Sciences Technologies / Material Science and Technology
2.05.02 Engineering sciences and technologies/Mechanics/Experimental mechanics
2.06 Engineering sciences and technologies / Systems and cybernetics
2.13 Engineering sciences and technologies / Process engineering
3.00 Medical Sciences
3.01 Medical sciences/ Microbiology and immunology
3.03 Medical sciences/ Neurobiology
3.04 Medical Sciences/Oncology
3.05 Medical sciences / Human reproduction
3.06 Medical sciences / Cardiovascular system
3.07 Medical sciences/Metabolic and hormonal disorders
3.08 Medical Sciences / Public Healt
3.08 Medical Sciences / Public Health
4.00 Biotechnical Sciences
4.01.02 Biotechnical sciences / Forestry, wood and paper technology / Wood technology
4.03 Biotechnical sciences / Plant production
4.04.03 Biotechnical sciences / Veterinarian medicine / Therapy and health prevention of animals
4.06 Biotehniške vede
4.06 Biotechnical sciences / Biotechnology
4.06.01 Biotechnical sciences-Biotechnology-Recombinant DNA technology
4.06.02 Biotechnical sciences / Biotechnology / Bio-engineering
4.06.04 Biotechnical sciences/Biotechnology/Microbe biotechnology


Receptors for toxins of plant pathogens

Losses in crop production due to plant diseases average 20 % worldwide and severely limit production, quality, and safety of food. The main culprits, besides viruses, are fungi, bacteria and oomycetes. Practice of crop protection has been progressively reoriented towards reduction of a number of active ingredients in pesticides to those that are more selective and l...

01. January 2016 - 31. December 2018 | 1.05 Natural sciences and mathematics/Biochemistry and molecular biology

Efficacy of bacteriophages for treatment of extracellular and intracelular bacterial infections of implantants

Goal of the project is to investigate possibility of bacteriophage therapy in periprosthetic joint infections (PJI) treatment. The number of joint implants is increasing every year, as they nearly eliminate pain and contribute significantly to better mobility of the patients affected with end stage joint derangements. Along with increasing number of patients with jo...

01. September 2020 - 31. August 2023 | 1-09 Natural sciences and Mathematics - Pharmacy

Inflammatory process in interstitial cystitis and evaluation of the influence of cannabinoid receptor agonists in urinary bladder - from cells to patients

Interstitial cystitis (IC) is a urinary bladder disorder with no obvious histopathology or bacterial infection. Its prevalence is up to 2% in females, diagnosed annually, and its incidence is increasing globally. Since the etiology of IC is poorly understood, this illness still lacks an efficient cure, as the current treatment is still not successful in more than a ...

01. September 2020 - 30. August 2023 | 3.03 Medical sciences/ Neurobiology

Role of APOBEC proteins in the oncogenesis of HPV viruses

Human papillomaviruses (HPV) are one of the most prevalent sensually transmitted pathogens, responsible for more than 5 % of all cancers in humans, including cervical cancer and HPV-associated head-and-neck cancer. APOBEC3 (A3) proteins are cytidine deaminases that are capable of DNA and RNA editing. DNA-editing activity represent a key part of the innate immune response to viral infections. Howev...

01. September 2020 - 31. August 2023 | 3.01 Medical sciences/ Microbiology and immunology

Structural insight into iodine metabolism

Iodine is the heaviest essential trace element required by the higher living organisms. It is incorporated in T3/T4 hormones responsible for regulation of basal metabolism of almost any cell. T3 and T4 hormones are produced in the thyroid gland. The thyroid hormone metabolism involves selenium containing deiodinases and additional selenoperoxidases and thioredoxin p...

01. January 2016 - 31. December 2018 | 1.05 Natural sciences and mathematics/Biochemistry and molecular biology

Selective mechanical removal of bacterial biofilms by conjugated magnetic nanoparticles

Biofilms are microbial communities protected by a self-synthesized layer of extracellular polymeric substance that form on surfaces. Biofilms protect the bacteria from the host immune system and enable them to persist in adverse environmental conditions. They are an important clinical and public health problem, as up to 80% of all bacterial infections in humans ar...

01. October 2022 - 30. September 2025 | 1-09 Natural sciences and Mathematics - Pharmacy

Bactericidal nanoblades: a proof-of-concept approach for bimodal chemo-mechanical eradication of persistent biofilms

Biofilms are complex microbial ecosystems formed by bacteria encased in their own matrix of extracellular polymeric substances that are bound to the surface. Biofilms offer several advantages to bacteria, such as hydration, resource acquisition, digestibility and protection from mechanical damage and antimicrobial agents. Bacteria can form biofilms on a wide variety...

01. December 2021 - 30. November 2024 | 3.08 Medical Sciences / Public Health

The Role and Potential Application of Immunomodulatory Mesenchymal Stem Cells in COVID- 19 Disease

The declared pandemic caused by new SARS-CoV-2 virus in 2020, did not catch the research organizations and pharmaceutical companies completely unprepared. Many scientific groups have already carried out research that was indirectly addressing the challenges facing the international health systems of today. In Slovenia, high level of scientific and professional healt...

01. October 2021 - 30. September 2024 | 3.01 Medical sciences/ Microbiology and immunology

Development of highly concentrated protein formulations and evaluation of absorption kinetics after subcutaneous administration

Over the past several decades, protein therapeutics, and monoclonal antibodies (MAbs) have contributed to better therapeutic success in a wide range of diseases. Especially formulations for subcutaneous administration are gaining in importance  and represent one of the most significant areas in the field of pharmaceutical industry. Subcutaneous administration p...

01. October 2021 - 30. September 2024 | 1-09 Natural sciences and Mathematics - Pharmacy

Recombinant probiotics as bio-alternative antimicrobial approach against Clostridioides difficile

Clostridioides difficile infections represent a growing and serious health threat, particularly for the elderly and immune-compromised patients in the hospital setting. C. difficile causes a spectrum of pathological conditions ranging from mild self-limiting diarrhea, to serious diarrhea, pseudomembraneous colitis and potentially lethal fulminant colitis. C. diffici...

01. October 2021 - 30. September 2024 | 4.06 Biotehniške vede