Cathepsins B and X in breast cancer stem cells – molecular targets and relevance for antitumor therapy
01. October 2021 - 30. September 2024 | 3.04 Medical Sciences/Oncology
Despite advances over the past years the treatment of breast cancer is still facing many challenges, among them overcoming cancer recurrence and avoiding therapy resistance are the main goals in the aim to improve patients’ status. Failure in antitumor therapy has been, among the phenotypically and functionally heterogenous population of cells with...
Tunneling nanotubes for innovative urinary bladder cancer treatments
01. January 2016 - 31. December 2018 | 3.04 Medical Sciences/Oncology
Scientific background and problem introduction Urinary bladder cancer is 6th among all cancers worldwide and 1/3 of urinary bladder cancer emerges as multifocal tumours at different sites of the urothelium, e.g. epithelium which represents effective blood-urine barrier. Treatment usually includes the resection of the tumours during the transurethral resection of the...
NOBIL - Novel Biomarkers in Leukemia
01. May 2018 - 30. April 2020 | 3.04 Medical Sciences/Oncology
The project NOBIL will therefore focus on the translational research in oncology to contribute to the discovery of novel biomarkers and innovative individualized therapeutic approaches to overcome the resistance of leukemia. The proposed project emerged from ongoing effort of academics and clinicians at Faculty of pharmacy (prof. Mlinarič-Raščan) and Institut...