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National projects

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1.03 Natural sciences and mathematics / Biology
1.04 Natural Sciences and mathematics/Chemistry
1.04.02 Natural sciences and mathematics / Chemistry / Structural chemistry
1.05 Natural sciences and mathematics/Biochemistry and molecular biology
1.07. Natural sciences and mathematics / Computer intensive methods and applications
1.09 Pharmacy
1-09 Natural sciences and Mathematics - Pharmacy
2.04 Ingeeniring Sciences Technologies / Material Science and Technology
2.05.02 Engineering sciences and technologies/Mechanics/Experimental mechanics
2.06 Engineering sciences and technologies / Systems and cybernetics
2.13 Engineering sciences and technologies / Process engineering
3.00 Medical Sciences
3.01 Medical sciences/ Microbiology and immunology
3.03 Medical sciences/ Neurobiology
3.04 Medical Sciences/Oncology
3.05 Medical sciences / Human reproduction
3.06 Medical sciences / Cardiovascular system
3.07 Medical sciences/Metabolic and hormonal disorders
3.08 Medical Sciences / Public Health
4.00 Biotechnical Sciences
4.01.02 Biotechnical sciences / Forestry, wood and paper technology / Wood technology
4.03 Biotechnical sciences / Plant production
4.04.03 Biotechnical sciences / Veterinarian medicine / Therapy and health prevention of animals
4.06 Biotehniške vede
4.06 Biotechnical sciences / Biotechnology
4.06.01 Biotechnical sciences-Biotechnology-Recombinant DNA technology
4.06.02 Biotechnical sciences / Biotechnology / Bio-engineering
4.06.04 Biotechnical sciences/Biotechnology/Microbe biotechnology

Range:

Selection and preparation of a dossier potentially neurotoxic chemical using in silico methods for the purpose of implementing the European chemical legislation REACH

The project is focused on the search for neurotoxic compounds in a group of chemicals that are used in industry in large quantities, using in silico methods. It is divided into four main tasks: setting up a set of chemicals, arranging their toxicological profiles, selecting candidates (one to five) by reviewing and comparing existing data and presenting a dossier fo...

01. November 2019 - 31. October 2020 | 1.04.02 Natural sciences and mathematics / Chemistry / Structural chemistry

Exploitation of a virus-borne small protein to combat antibiotic resistance in Staphylococcus aureus

The development of drug‑resistant bacteria is an unavoidable outcome of widespread antibacterial chemotherapy of infectious diseases. Drug discovery programs directed against proteins considered essential for in vivo bacterial viability have yielded few new therapeutic classes of antibiotics, therefore treatment options for combating bacteria resistant to multiple d...

01. July 2019 - 31. December 2022 | 4.06.04 Biotechnical sciences/Biotechnology/Microbe biotechnology

Improvement of immunotherapeutic potential of NK cells through modulation of cystatin F

The effectiveness of conventional therapeutic modalities, including chemotherapy and radiotherapy, is limited due to drug resistance acquired by tumor cells during systemic treatment. Moreover, convenient antitumor drugs are practically ineffective against cancer stem cells, which represent a dormant pool of cells able to induce tumor recurrence. Cancer immunotherap...

01. July 2019 - 30. June 2022 | 4.06 Biotechnical sciences / Biotechnology

Selective extraction of high value molecules from forest products processing residues in the speciality chemicals sector

Forest-based industries, especially pulp and paper industries, produce huge quantities of bark during primary processing activities. In 2017 alone, the European pulp and paper industry used close to 149 million cubic meters of wood. The bark reduces the quality of wood products and is removed and mainly burned for energy production. In pulp and paper industries, a w...

01. July 2019 - 30. June 2022 | 4.01.02 Biotechnical sciences / Forestry, wood and paper technology / Wood technology

Protein interaction atlas for prediction of genetic variations involved in drug interactions and disease development

Computer intensive methods and applications is extremely propulsive area of scientific research in which the use of supercomputers and computer clusters is used to solve the most demanding computational problems in theoretical and applied research in natural and technical sciences. We deal with solving of various types of problems, such as, structure and dynamics of...

01. July 2019 - 06. January 2022 | 1.07. Natural sciences and mathematics / Computer intensive methods and applications

Structural insight into the mechanism of Clostridium difficile surface formation

The cell wall of Gram-positive bacteria is composed of proteins and peptidoglycan with the protruding secondary polysaccharides, which differ in the chemical composition and structure among various species. The cell wall secondary polysaccharides are covalently attached to the peptidoglycan and can account for more than a half of the total cell wall mass. They form ...

01. July 2019 - 30. June 2023 | 1.05 Natural sciences and mathematics/Biochemistry and molecular biology

Biotechnological potential of selected microorganisms from Sečovlje Saltpans for application in cosmetics products

Blue Growth (BG) and sustainable blue strategy, including Marine (blue) biotechnology (MBT), are the long-term strategies to support sustainable growth. The global market for MBT has the potential to reach €5.5 Billion by 2025 and Europe is recognised as a high-potential region with largely unexplored marine resources. Since the global population`s median age i...

01. October 2022 - 30. September 2025 | 4.06 Biotechnical sciences / Biotechnology

Quantitative light scattering spectroscopy as a process analytical technology in pharmaceutical manufacturing

01. October 2022 - 30. September 2025 | 2.06 Engineering sciences and technologies / Systems and cybernetics

MitoCan - Preclinical development of new Mitochondrial ion channel inhibitors for Cancer therapy

Ion channels are now considered unconventional, promising oncological targets, whose expression is often altered in cancer cells and which areemerging as critical players in tumorigenesis. The idea of targeting Kv1.3 ion channels directly in mitochondria, whose function critically depends onion fluxes and which are crucial for both cell survival and apoptosis, could...

01. October 2022 - 30. September 2025 | 1-09 Natural sciences and Mathematics - Pharmacy

Nanofibers for codelivery of selected microbiota cocktails and antimicrobials for local treatment of vaginal infections

Scientific background and problem identification. Vaginal infections are the most common reason women seek medical help and can cause serioushealth consequences, such as pelvic inflammatory disease, increased risk of sexually transmitted infections, and adverse pregnancy outcomes. Themost common vaginal infections are bacterial vaginosis and vaginal candidiasis, bot...

01. October 2022 - 30. September 2025 | 1-09 Natural sciences and Mathematics - Pharmacy