Research programmes
Range:
Advanced immunological drugs and cell-based approaches in pharmacy
The development of safe and effective vaccines against infectious diseases such as SARS-CoV2, Zika, malaria, Ebola and the emerging zoonoses is a major goal in global public health. Also, cancer clearly remains one of the leading causes of disease and mortality worldwide. Recent advances in immunotherapy and cell therapy established them as potential new modalities ...
Medicinal chemistry - drug design, synthesis and evaluation
The long-term goal of the research programme is the discovery of new bioactive small molecules with a potential for development into drugs for use in important therapeutic areas through combined medicinal chemistry approaches. In the next period, the research programme will focus on the discovery and rational design, synthesis and biological evaluation of molecules ...
Pharmaceutical biotechnology: Science for health
Cancer, neurodegenerative and immune diseases represent a great health and social burden for our society. Due to prolongation of life expectancy the burden of these predominantly age-related diseases is anticipated to be even greater in the future. To avoid the collapse of the health care system, new, more effective therapy strategies are urgently needed. Our ...
Genes, hormones and personality changes in metabolic disorders
Our programme is based on activities and achievements in the last two decades in the field of chronic metabolic disorders such as osteoporosis and bone metabolism, polycystic ovary syndrome (PCOS), diabetes type 2 (and to a lesser degree type 1) and insulin resistance as a common component of the last two disorders. The majority of our activities will be further res...
Medicinal chemistry - drug design, synthesis and evaluation
The long-term goal of the research programme is discovery of new bioactive small molecules with a potential for development to drugs in important therapeutic areas through combined medicinal chemistry approaches. In the next period the research programme will focus on discovery and rational design of bioactive molecules exerting their action on validated drug targets, their synthesis and bio...