System for liquid chromatography with mass spectrometer (LC-MS)

Contact:

Prof. Janez Ilaš, M. Pharm., Ph. D.

Access:

Equipment is available at the Faculty of Pharmacy, Aškerčeva 7, 1000 Ljubljana. Public access to the equipment is not forseen. In any case one has to agree the details of an eventual access with its superviser which has to be present through whole agreed working time on the equipment.

Intended Purpose:

Apparatus for the identification and quantification of active substances, synthetic products, natural compounds, peptides and metabolites of active substances in complex samples Thermo Orbitrap mass spectrometer specifications: 1. Model: Exactive ™ Plus Orbitrap Mass Spectrometer type of mass detector: Orbitrap measuring range m / z: 50-6000 m / z - Mass resolution: 140 000 FWHM - mass accuracy: <1 ppm with internal calibration, <3 ppm with external calibration, Ion sources: - ESI: Electrospray Ionization ion source - APCI :Atmospheric Pressure Chemical Ionization ion source 2. UHPLC Thermo Scientific UltiMate ™ 3000 Liquid Chromatograph specifications: - binary pump capable of operating at a pressure of up to 1034 bar at flow rates up to 8 mL / min - sampling rate of UV-DAD: up to 200Hz.

Description of equipment:

Apparatus for the identification and quantification of active substances, synthetic products, natural compounds, peptides and metabolites of active substances in complex samples.

Price of equipment use

Use is €73,46 per hour.

Research Equipment ( co)funded by the Slovenian Research Agency.