Diffusion cells for release and dermal absorption evaluation with an automated sampling and dry heat system

Contact:

Assist. prof. Mirjam Gosenca Matjaž, M. Pharm., Ph. D.

Access:

The equipment is available at the Faculty of Pharmacy, Aškerčeva 7, 1000 Ljubljana. Possible access by agreement with the administrator. Due to the specificity of the equipment, the equipment administrator must be present at all times when working on the equipment.

Intended Purpose:

Diffusion cells with an automated sampling system enable release (IVRT; in vitro release test) and permeability (IVPT; in vitro permeation test) testing in the context of development and characterization or therapeutic equivalence evaluation of (trans)dermal formulations exhibiting a wide range of viscosities.

Description of equipment:

• RDS12Q: Teledyne Hanson Phoenix RDS
• VDCM12: Set of vertical diffusion cells of medium size
• DM-PC: Control unit with data acquisition software